I recently noticed that Amazon Prime Video (Six Feet Under, for the millionth time, natch), was doing an odd triple flicker when playing back in fullscreen mode within an updated Chrome browser on an Early 2015 Macbook Pro running Mojave 10.14.6. The fix seems to be turning off hardware acceleration within Chrome. Playback seems clear after that. YMMV. Steps:

1. Click the three dots on the upper right of the Chrome Toolbar.
2. Click Settings
3. Search “hardware”
4. Toggle of Use Hardware Acceleration.
5. Chrome will force a relaunch of the Browser.